Just works no drama
I bought the 11-36 version to use on my 8100 ultegra bike for a sub 1:1 climbing ratio. This is technically out of spec for the ultegra rear mech, but after a small b screw adjustment it is working without any issue. The ultegra cage is shorter, so maybe chain wrap could be an issue, but using the auto shift function prevents any extreme cross gears where chain length might be a concern. This 105 cassette does not have the HG+ teeth profile, but I honestly cannot tell any difference compared to my ultegra cassette while riding.